Protein Modification Reagents
Medchemexpress LLC Methyltetrazine-PEG5-NHS ester | 1802907-92-1 | 97.0% | C24H31N5O9 | 100 MG
Methyltetrazine-PEG5-NHS ester is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are molecules composed of two distinct ligands connected by a linker. These molecules harness the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used as a PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Selectively degrades target proteins via the ubiquitin-proteasome system
Medchemexpress LLC Dspe-PEG-SH | 90.0% | 1,000 Da | 50 MG
Thiol-terminated DSPE-PEG-SH (MW 1000) is an amphiphilic pegylated phospholipid composed of a DSPE lipid anchor linked to an approximately 1,000 Da polyethylene glycol chain that ends in a sulfhydryl group. It is intended for formulation of PEGylated liposomes and lipid nanoparticles and for surface functionalization or bioconjugation using thiol-specific chemistries.
- Thiol terminal for conjugation to gold, maleimide, or crosslinkers.
- Amphiphilic structure suitable for liposome and nanoparticle formulation.
- PEG chain ~1,000 Da provides steric stabilization and improved circulation.
- Typical purity around 90.0% as supplied.
- Soluble in common organic solvents used for lipid formulation.
- Packaged in small research quantities for laboratory use.
Medchemexpress LLC Mal-PEG4-Val-Cit-PAB-PNP | 2112738-09-5 | 871.89 | C40H53N7O15 | 5 MG
Mal-PEG4-Val-Cit-PAB-PNP is a protease-cleavable, four-unit polyethylene glycol (PEG4) ADC linker containing a maleimide reactive group and a Val-Cit-PAB cleavable spacer. It is used in the synthesis of antibody-drug conjugates to provide protease-sensitive release of payloads.
- Protease-cleavable PEG4 linker useful for ADC synthesis.
- Maleimide reactive group enables thiol conjugation to antibodies.
- Val-Cit-PAB spacer provides protease-sensitive payload release.
- Soluble in DMSO (125 mg/mL) and formulatable for in vivo use (solubility ≥ 2.08 mg/mL with recommended solvent systems).
- Storage: protect from light; in solvent -80°C for 6 months, -20°C for 1 month.
- For research use only; not fully validated for medical applications.
![Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)-folate] | 95.7% | 5000 (average) | 25 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000281640.png-250.jpg)
Medchemexpress LLC 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[poly(ethylene glycol)-folate] | 95.7% | 5000 (average) | 25 MG
DSPE-PEG-Folate (MW 5000) is a pegylated lipid conjugate in which a DSPE lipid anchor is linked to a poly(ethylene glycol) chain terminated with folic acid. It is supplied as a solid and is formulated for use in liposomes, micelles, and other nanoparticle systems to enable folate receptor-mediated targeting and uptake.
- Provides folate receptor targeting for enhanced cellular uptake.
- Contains a DSPE lipid anchor for stable membrane insertion.
- Uses a PEG 5000 chain to improve circulation and reduce nonspecific clearance.
- High purity supports reproducible nanoparticle formulation.
- Supplied as a solid for convenient storage and handling.
Medchemexpress LLC Ethanol, 2-(2-azidoethoxy)-, 1-(4-methylbenzenesulfonate) | 182347-24-6 | MFCD27946436 | 99.8% | 285.32 g/mol | C11H15N3O4S | 250 MG
N3-PEG2-Tos is a bifunctional PEG-based linker bearing an azide and a tosylate, designed for use as a small building block in click chemistry and bioconjugation. The product is supplied as a colorless to light yellow liquid with high analytical purity and defined storage recommendations for reliable handling in synthesis and research workflows.
- Azide functional group enables copper-catalyzed azide-alkyne cycloaddition.
- Tosylate leaving group allows nucleophilic substitution for linker installation.
- Small PEG2 spacer provides flexibility and solubility in conjugates.
- High purity (≈99.8%) supports analytical and synthetic applications.
- Stable under recommended storage conditions to preserve integrity.
Electron Microscopy Sciences Carbowax Polyethylene Glycol, PEG 400 viscous liquid, 25322-68-3, 450ml
Molecular Formula H(OCH2CH2)nOH, Carbowax Polyethylene Glycol is an embedding medium for microscopy and histochemistry.
Sino Biological Anti-MMAE Antibody, Mouse MAb
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with MMAE conjugated to BSA. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
eMolecules 2093152-86-2 | N-(Amino-PEG5)-N-bis(PEG4-acid), HCl salt | Broadpharm | MFCD30723284 | 776.915 | C34H68N2O17 | 95.000 | NCCOCCOCCOCCOCCOCCN(CCOCCOCCOCCOCCC(O)=O)CCOCCOCCOCCOCCC(O)=O | 500mg | 340376983
N-(Amino-PEG5)-N-bis(PEG4-acid), HCl salt | Broadpharm | 2093152-86-2 | MFCD30723284 | 776.915 | C34H68N2O17 | 95.000 | NCCOCCOCCOCCOCCOCCN(CCOCCOCCOCCOCCC(O)=O)CCOCCOCCOCCOCCC(O)=O | 500mg | 340376983
![eMolecules 1263166-93-3 | endo-BCN-PEG2-amine | Broadpharm | MFCD19705418 | 324.421 | C17H28N2O4 | 95.000 | NCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 500mg | 533795522](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502203458.JPG-250.jpg)
eMolecules 1263166-93-3 | endo-BCN-PEG2-amine | Broadpharm | MFCD19705418 | 324.421 | C17H28N2O4 | 95.000 | NCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 500mg | 533795522
endo-BCN-PEG2-amine | Broadpharm | 1263166-93-3 | MFCD19705418 | 324.421 | C17H28N2O4 | 95.000 | NCCOCCOCCNC(=O)OC[C@@H]1[C@@H]2CCC#CCC[C@H]12 | 500mg | 533795522
Medchemexpress LLC Mal-PEG24-NHS ester | 2226733-37-3 | MFCD11041160 | 95.0% | 1394.55 | C62H111N3O31 | 5 MG
Mal-PEG24-NHS ester is a bifunctional polyethylene glycol (PEG) linker containing a maleimide and an N-hydroxysuccinimide (NHS) ester. It is designed for bioconjugation and PROTAC synthesis, enabling selective coupling between thiol and primary amine functionalities while improving solubility and molecular flexibility. The compound is an oil (colorless to light yellow) with molecular weight 1394.55 and formula C62H111N3O31.
- Enables selective maleimide-thiol coupling to modify cysteine residues.
- Provides NHS-ester reactivity for efficient labeling of primary amines.
- PEG24 spacer increases solubility and reduces steric hindrance.
- Suitable for assembling heterobifunctional molecules such as PROTACs.
- Stable under sealed storage at -20 °C; in solvent, store at -80 °C for long-term stability.
- Supplied in small research quantities suitable for synthetic applications.
eMolecules 1643594-31-3 | Acid-PEG13-NHS ester | Broadpharm | MFCD27952889 | 787.850 | C34H61NO19 | 0.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 100mg | 263744727
Acid-PEG13-NHS ester | Broadpharm | 1643594-31-3 | MFCD27952889 | 787.850 | C34H61NO19 | 0.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O | 100mg | 263744727